This system facilitates the simultaneous detection of multiple RNA targets within a single tissue section or cell sample. Employing a signal amplification strategy coupled with fluorescent labeling, it provides a sensitive and specific method for visualizing gene expression patterns. For example, researchers can use this technology to identify co-expression of several genes within distinct cell populations within a tumor microenvironment.
This methodology is valuable in numerous research areas. Its ability to precisely locate and quantify multiple RNA transcripts allows for a deeper understanding of complex biological processes. This is particularly beneficial in studies of disease mechanisms, drug target validation, and biomarker discovery. The technique overcomes limitations of traditional methods, such as immunohistochemistry, by directly visualizing RNA and enabling the analysis of multiple targets concurrently.
